Anti-oncogenic potential of the eIF4E-binding proteins
نویسندگان
چکیده
منابع مشابه
Interaction of viral oncogenic proteins with the Wnt signaling pathway
It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenes...
متن کاملOncogenic Potential of Hepatitis C Virus Proteins
Chronic hepatitis C virus (HCV) infection is a major risk factor for liver disease progression, and may lead to cirrhosis and hepatocellular carcinoma (HCC). The HCV genome contains a single-stranded positive sense RNA with a cytoplasmic lifecycle. HCV proteins interact with many host-cell factors and are involved in a wide range of activities, including cell cycle regulation, transcriptional r...
متن کاملRegulation of Aml Propagation by Oncogenic Rna Binding Proteins
1 All articles published in this journal are protected by copyright. 2014 – POST-TRANSCRIPTIONAL REGULATION OF AML PROPAGATION BY ONCOGENIC RNA BINDING PROTEINS Takahiro Ito, Ayuna Hattori 1 1 University of Georgia Acute myelogenous leukemia is characterized by uncontrolled propagation of abnormal myeloid cells with a limited capacity to differentiate into mature cells. Recent studies have show...
متن کاملSteroid/thyroid receptor-like proteins with oncogenic potential: a review.
Mutated or truncated forms of certain members of the steroid/thyroid receptor superfamily have oncogenic potential. The aberrant forms compete with the normal receptor for binding to the responsive element on the DNA and thus interfere negatively with the normal transcription control mechanism. Oncogenes that arise from dominant negative mutations may therefore be called "dononcs," to distingui...
متن کاملThe Tall Tale of the Helicobacter pylori Blood Group Antigen Binding Proteins
The features of Helicobacter pylori adhesins, their interactions with their host counterparts, regulated and selective gene expressions are amongst the many clever strategies this microorganism undertakes to survive the otherwise sterile gastric milieu. The ingenious crafting of these interactions and the respective host reactions govern, in part, an array of consequences ranging from asympto...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncogene
سال: 2012
ISSN: 0950-9232,1476-5594
DOI: 10.1038/onc.2012.116